research download r21.0.001

Download SPD Research Tool

SPD Research Tool is a small utility for Windows Computer that allows you to flash the stock firmware (PAC) on Spreadtrum/Unisoc Powered smartphones, Feature Phones, and tablets.

Here on this page, we have shared the latest version and the previous versions of the SPD Research Tool.

Features of SPD Research Tool

Easy Interface :

It comes with an easy interface, allowing you to quickly select the stock firmware by clicking the Load Firmware button. It also allows you to access the Tool’s settings, including Flash Operations, Multi Languages, and LCD Configure.

Flash Stock Firmware :

It allows you to flash the .pac based stock firmware on Spreadtrum/Unisoc Chipset powered smartphones and tablets. Therefore, the Tool can be more convenient and valuable than the SPD Upgrade Tool.

Flash Recovery :

It allows you to flash the Stock recovery on your Spreadtrum/Unisoc Devices. You can also flash the custom recovery or any root package on your Spreadtrum device.

Other Options :

It allows you to choose the device’s Multi-Language option (requires NV file), Configures the LCD settings (may need user image file), MCP type, Volume Frequency Tuning, Read Active Flash, and Erases, Writes Active Flash.

Download SPD Research Tool (Spreadtrum)

SPD Research Tool is compatible with all versions of Windows OS, including Windows XP to Windows 11 (x32 or x64 bit). If in case you were looking for the latest version of the Research Tool, then use the following links to get it on your computer:

R2.9.6011 : SPD_Research_Tool_R2.9.6011.zip

R2.9.7002 : SPD_Research_Tool_R2.9.7002.zip

R2.9.7003 : SPD_Research_Tool_R2.9.7003.zip

R2.9.7006 : SPD_Research_Tool_R2.9.7006.zip

R2.9.7007 : SPD_Research_Tool_R2.9.7007.zip

R2.9.7008 : SPD_Research_Tool_R2.9.7008.zip

R2.9.7009 : SPD_Research_Tool_R2.9.7009.zip

R2.9.7017 : SPD_Research_Tool_R2.9.7017.zip

R2.9.8004 : SPD_Research_Tool_R2.9.8004.zip

R2.9.8005 : SPD_Research_Tool_R2.9.8005.zip

R2.9.9005 : SPD_Research_Tool_R2.9.9005.zip

R2.9.9009 : SPD_Research_Tool_R2.9.9009.zip

R2.9.9015 : SPD_Research_Tool_R2.9.9015.zip

R2.9.9016 : SPD_Research_Tool_R2.9.9016.zip

R2.9.9017 : SPD_Research_Tool_R2.9.9017.zip

R2.10.1001 : SPD_Research_Tool_R2.10.1001.zip

R2.10.1003 : SPD_Research_Tool_R2.10.1003.zip

R3.0.0001 : SPD_Research_Tool_R3.0.0001.zip

R3.0.900 : SPD_Research_Tool_R3.0.900.zip

R3.15.4901 : SPD_Research_Tool_R3.15.4901.zip

R4.0.0001 : SPD_Research_Tool_R4.0.0001.zip

R6.0.0001 : SPD_Research_Tool_R6.0.0001.zip

R7.0.0001 : SPD_Research_Tool_R7.0.0001.zip

R8.0.0001 : SPD_Research_Tool_R8.0.0001.zip

R17.0.0001 : SPD_Research_Tool_R17.0.0001.zip

R19.0.0001 : SPD_Research_Tool_R19.0.0001.zip

R21.0.0001 : SPD_Research_Tool_R21.0.0001.zip

R22.19.1301 : SPD_Research_Tool_R22.19.1301.zip

R23.0.0001 : SPD_Research_Tool_R23.0.0001.zip

R23.19.3301 : SPD_Research_Tool_R23.19.3301.zip

R23.19.5101 : SPD_Research_Tool_R23.19.5101.zip

R24.0.0003 : SPD_Research_Tool_R24.0.0003.zip

[*] How to Use : If you want to learn to use the Research Tool to Flash Stock firmware, then head over to How to use SPD Research Tool page.

[*] Alternative : SPD Upgrade Tool and SPD Factory Tool are the best alternative to Research Tool. Both tools are officially created by Spreadtrum and comes with same interface and features.

[*] How to Write IMEI : After flashing (installing) the stock firmware on Spreadtrum Device, you may need to flash (install) the IMEI. To flash the IMEI on your Spreadtrum device, checkout the WriteIMEI and Read&Write Tool .

ASMobile Downloader for Windows

March 12, 2024

MIO Kitchen for Windows, Linux and macOS

March 7, 2024

RockChip Android Tool for Windows

March 6, 2024

HQ MTK Customer Download Tool for Windows

February 26, 2024

Tiny Fastboot Script for Windows

SPD Research Tool R21.0.0001

The SPD Research Tool R21.0.0001 is a Portable Application Software for Computer. It Helps to Easily SpreadTrum Mobile Phone install Firmware Flash File. the Also Support Unlock Patten lock and any type of software issue.

Below are the links to the SPD Research Tool Setup File on this Page Files zip Package SPD USB Driver, and installation Solutions.

SPD Research Tool R21.0.0001 Information

SPD Research Tool helps you to write “.Pac” firmware (flash file) and ROM mobile phone or tablet on your SpreadTrum mobile phone. It also supports unlocking factory reset (FRP) SPD CPU for smartphones or tablets.

File Name: SPD_Research_Tool_R21.0.0001.zip File Size: 5 MB Computer Compatibility : Windows 7,8,10 (x32 or x64)

How To Install and Using SPD Research Tools?

Download SPD Research Tool R21.0.0001 on your laptop and PC.
Download The SPD USB Driver Zip File Package Extract it.
Dabble click choose menu the driver and install.
After opening the SPD Research (.exe).
Now “.pac” Zip File package Extract it.
After loading button click on the Firmware.
Now see Locate Firmware (flash .pac file).
Then, click on Start Button.
Flashing few time to finish not unplug the USB Cable at this time.

Also Download: SPD Research Tools (all version)

Readme Once

[*] Knowledge: You Need To Flash Your Device. Must Flashing Be Had Knowledge? We are Not Liable for Any Damage To Your Mobile Phone.

[*] Why Needs Backup: You, Will, Go To Flash Android Mobile Phone But Need a Backup Of Your Device. After Flashing is Completed Then Loss Your All Data.

[*] Credits: : SPD Research Tools is made and circulated by UNISOC Technologies deserve. Thus, they merited the absolute recognition for sharing the Flash Tool free of charge.

[*] SPD USB Driver: You Need a SpreadTrum USB Driver To Connect Your Phone To The PC/Laptop then Download it Here SPD USB Driver .

[*] Other FLASH TOOL: It Is Very Need Firmware are Able To Flashing and Unlock Your SpreadTrum Mobile Click To SPD Factory Tool and SPD Upgrade Tool .

Facebook SDK

Spd research tool r21.0.0001 download.

This Tool Work Only Spd Cpu

Download Link :- Click Here

Post By GSM Rakesh

You might like

SPD Research Tool – Download (All Versions) SPD Flash Tool

Download SPD Research Tool SmartPhone Flash Tool works for Spreadtrum chipset stock firmware flash file install or flash easily.

if you need the latest version and old version SPD Research Tool then you have come to the right place. you need updated version SPD flash tool and try to Install file on your Spreadtrum devices need download tools and flashing guide this articles for you.

Feature Of SPD Research Tool

It allows flashing PAC firmware only to Spreadtrum devices, allows flash Recovery or custom recovery load Pac file, it allows verifying test the external memory, Ram, Emmc, Nand, it allows format device auto and manual, hard resat and ETC.

SPD Research Tool Download

Spd Flash Tool allows you to flash the pac Stock ROM on your Spreadtrum powered devices and also helps you to remove screen lock and FRP lock on your smartphone.

Tools Name: SPD Research Tool (SPD Flash Tool) Compatible: Windows Computer Requirements: Pc, Laptop, Usb Cable, SPD Driver, Pac File

How To Use SPD Research Tool

Download and extract SPD Flash Tool on your computer.
Extract Your Stock ROM Firmware Flash File.
Install Spreadtrum Cpu USB Driver On Your Computer.
Open SPD Flash Tool Folder ( UpgradeDownload.exe ).
Locate the Right Pac Stock Firmware Flash File.
After Locate Firmware Then Click the Start Downloading button .
Now, Connect Your Spreadtrum Device in Flash Mood.
Flashing completed you have seen a passed notice.

Download Factory / Research / Upgrade Download Tools (all versions)

Factory download tool versions.

SPD Factory Download Tool R2.9.9015 https://mega.nz/#!G983gSrK!fcFosbR6RKAWD...xT_Cxip4tw
SPD Factory Download Tool R19.17.4301_P1 https://mega.nz/#!8GxgGQTB!Vg5BjSySGylPm...Ek4Dhefoi4
SPD Factory Download Tool R21.0.0001 https://mega.nz/#!St9lwQZZ!eACDlJ-E_Hbft...-_Uiw0jIY8
SPD Factory Download Tool R23.0.0001 https://mega.nz/#!TwFSzYqS!CazEkP5KbdcS5...rE8mgKxJs0
SPD Factory Download Tool R24.0.0003 https://mega.nz/file/e98mDALb#1aeLDG4OhR...ZcxtQv21X0
SPD Factory Download Tool R25.20.3901 https://mega.nz/file/dxRUTTYZ#gHBDk34UMn...dv2cHSIdks
SPD Factory Tool R27.23.1902 https://mega.nz/file/glZxmCaa#MCEu2zdpL5...qnPhu98cMo

Research Download Tool Versions

SPD Research Download Tool R2.9.7002 https://mega.nz/#!fpV3mYaZ!HkuGCIGD7zmFA...iHZ4NrvYOw
SPD Research Download Tool R2.9.7003 https://mega.nz/#!ZxwV0DxK!s_5KEF2eoSddG...LDtdlh6umU
SPD Research Download Tool R2.9.7006 https://mega.nz/#!g15wyAxZ!-kbXK4CRF-xET...6icUfumZOM
SPD Research Download Tool R2.9.7007 https://mega.nz/#!1hglkLiD!4Thibrfkp9nvl...16eGZdM9fU
SPD Research Download Tool R2.9.8004 https://drive.google.com/open?id=0B4S-Z7...GFzcFBWaG8
SPD Research Download Tool R2.9.8005 https://drive.google.com/open?id=0B4S-Z7...UxaSmluczA
SPD Research Download Tool R2.9.9005 https://drive.google.com/open?id=0B4S-Z7...jRpOVZfVXc
SPD Research Download Tool R2.10.1001 https://mega.nz/#!0swF1LTI!cS_emYeEFpWr3...p8HpHuKDkA
SPD Research Download Tool R3.0.0001 https://mega.nz/#!LlFHGCSQ!jO-sOUIgVRLVQ...APNpRu-Azg
SPD Research Download Tool R4.0.0001 https://mega.nz/file/lJEFhKzB#dwjKpA2KyC...Z-HA0SQ_Jk
SPD Research Download Tool R6.0.0001 https://mega.nz/#!jlEDzAIB!cZlDa9R6F-f5e...ppPaWif2P0
SPD Research Download Tool R7.0.0001 https://mega.nz/#!7sVgwSQZ!WIHnJMVrqLd_v...yh5gsqFjKE
SPD Research Download Tool R8.0.0001 https://mega.nz/#!GpNWFK6I!aN4wTHu3YWzO_...KBc2DSSaN8
SPD Research Download Tool R17.0.0001 https://mega.nz/#!j1V2FSgD!QIX9vUS8wYwt_...7BBPerU6Vk
SPD Research Download Tool R19.0.0001 https://mega.nz/#!mgdnkIiZ!Ffcw1tuu70m4p...Tso1Da-J6k
SPD Research Download Tool R21.0.0001 https://mega.nz/#!HodB3aBQ!yWAQkWkxaHHj0...VucwqPMePQ
SPD Research Download Tool R22.19.1301 https://mega.nz/#!jp9GHIhA!qk67F5AE71qVA...EyZW0hDlAQ
SPD Research Download Tool R23.0.0001 https://mega.nz/#!WpMABIiS!NQx9aua1GIe0S...-fvwu__vSg
SPD Research Download Tool R23.19.3301 https://mega.nz/#!PtdhCCaD!1Q0CY14itwtsc...V1Euow5hW0
SPD Research Download Tool R24.0.0003 https://mega.nz/file/mw1EjI5b#WtIr3T1vep...hEUE_ORlq8
SPD Research Download Tool R25.20.3901 https://mega.nz/file/8lZzECZL#5lWkfej5E9...t043ZFHy4A
SPD Research Download Tool R27.23.1902 https://mega.nz/file/14pQnIjA#2cRz1Non6H...N7ChXnNWBo

Upgrade Download Tool Versions

SPD Upgrade Download Tool R2.9.6004 https://drive.google.com/open?id=0B4S-Z7...1h2RkZKSlE
SPD Upgrade Download Tool R2.9.7001 https://drive.google.com/open?id=0B4S-Z7...0ZVejkwSmM
SPD Upgrade Download Tool R2.9.7003 https://drive.google.com/open?id=0B4S-Z7...ERqZGdJQXM
SPD Upgrade Download Tool R2.9.7006 https://drive.google.com/open?id=0B4S-Z7...UtSZlg0b3c
SPD Upgrade Download Tool R2.9.7007 https://drive.google.com/open?id=0B4S-Z7...EVfUWhvU00
SPD Upgrade Download Tool R2.9.7008 https://drive.google.com/open?id=0B4S-Z7...0FKQ245bVE
SPD Upgrade Download Tool R2.9.9001 https://drive.google.com/open?id=0B4S-Z7...mVzTjJPVzA
SPD Upgrade Download Tool R2.9.9008 https://drive.google.com/open?id=0B4S-Z7...k5NbVI2dWM
SPD Upgrade Download Tool R2.9.9009 https://drive.google.com/open?id=0B4S-Z7...UFrS1lBYzQ
SPD Upgrade Download Tool R2.9.9015 https://drive.google.com/open?id=13gOsfR...TcDWiTQT71
SPD Upgrade Download Tool R3.0.0001 https://drive.google.com/open?id=0B4S-Z7...1dISDZ2Nm8
SPD Upgrade Download Tool R4.0.0001 https://mega.nz/#!e01x3aLa!Jiv4urBkv65Hk...t3NLdCNJg4
SPD Upgrade Download Tool R17.0.0001 https://drive.google.com/open?id=0B4S-Z7...Gt0NWZ6UzQ
SPD Upgrade Download Tool R19.0.0001 https://drive.google.com/open?id=1EVi9yj...0GM3EyVgmN
SPD Upgrade Download Tool R21.0.0001 https://mega.nz/#!60lSxARK!gNKkmNOn8ionE...MTZeK5mAAI
SPD Upgrade Download Tool R22.0.0001 https://mega.nz/#!iskW1IiA!JkaMGmiiPAa2v...40H1ycqU5c
SPD Upgrade Download Tool R23.0.0001 https://mega.nz/#!vwESDAJJ!_Vl6SxO3ikdQQ...SEo5FzUsXY
SPD Upgrade Download Tool R23.19.4001 https://mega.nz/#!69d2lQyb!asEpvI8sgc6Ii...SSJGYMwg_c
SPD Upgrade Download Tool R24.0.0003 https://mega.nz/file/6tUGlQqC#JrlCOkr9PB...Bt4uVFAfEE
SPD Upgrade Download Tool R25.20.3901 https://mega.nz/file/A4ozkIjK#ApcW1SCZ3T...YuULgzgteM
SPD Upgrade Download Tool R26.21.2801 https://mega.nz/file/d1JkRQ5L#aVDN4o_FSw...Mvs-NQWe00
SPD Upgrade Download Tool R27.23.1902 https://mega.nz/file/p8IgQDTI#2mgzY8jK3p...8N9q_AYlbU

(25-01-2021, 04:54 AM) haydar.rewwin ...

(12-02-2021, 01:37 PM) siamese007 Hello Sir and friends, Thank you sharing all the 3 tools for Unisoc. I downloaded and run R24 of all the 3 tools but got error missing some files .dll But R23 run fine for me. Is there anything I can do to fix these error of missing some files .dll?

(13-02-2021, 12:58 AM) X3non what dll is missing? maybe you need to install microsoft visual c++ redistributable

(13-02-2021, 06:02 AM) siamese007 Here are the screenshots of the errors. https://imgur.com/AZS9g5p https://imgur.com/JfOtNI8 I've installed MS Visual C++ 2005 2008 2010 2012 2013 2015. Not sure which ones that I missed.

SPD Flash Tool - Download SPD Upgrade Tool

SPD flash tool , also known as SpreadTrum flash tool is the newly developed tool for flashing PAC/ P5C firmware files for Android devices. The latest SPD upgrade tool is packed with the newest patches and fixed bugs from the earlier versions. SPD Flash is very user-friendly and simple to use. All users can download the latest version through the direct download links on the download section. Spreadtrum Upgrade Tool is very similar to SP Flash Tool but supports flashing the device with SPD CPU [eg: iTEL Android device] while SP Flash supports mobile devices with MTK CPUs. Spreadtrum chipsets only compatible with the SPD Upgrade Tool to flash PAC and/ or P5C firmware files. Bin packet load error widely encounters and an upgraded tool version released to correct errors entitled SPD Research Tool. Write IMEI is needed at the end of the flash and use WriteIMEI or Read&Write Tool is recommended.

What is SPD Research Tool?

Flashing Spreadtrum chipset installed smartphone is the major task of SPD Research Tool. This is an upgraded version of the SPD flash tool released by the same developer. This tool will help you to flash stock firmware/ recovery, custom recovery or the root package on Spreadtrum devices. Choose multi-languages on Androids, configure the LCD settings, MCP Type, Read/ Erase/ Write active flash, volume frequency tuning are alternative features. If the device reports "Bin Packet load error" with SPD flash tool, try flash firmware with SPD Research Tool. The research tool replaces the SPD upgrade tool and inbuilt with the same features also officially created by Spreadtrum Communications Inc.

Special Notice : The SPD Research Tool is compatible only with "PAC" firmware. None of "P5C and PAC.5C" firmware types are flashed by the SPD Research Tool.

SpreadTrum Flash tool New Features

Simple user interface.

The simple interface provides the easy firmware load ability and flashing the firmware.

Flash .PAC firmware

Just add the firmware and click "Start Download" to start the flashing the device using PAC firmware on Android smartphones and tablets.

Flash P5C Firmware

Supports flashing P5C firmware, a rare firmware found only in a few devices.

Supports Multi Languages

Facility to add more languages and configurations on the device OS and work only when special NV and userimg files are added to supports the configuration of the device.

Download SPD Flash Tool

The newly released SPD flash tool R21.0.0001 is now available to download. If any matter, use the latest version of SPD Research Tool to flash ".pac" firmware. Download and install the latest version of Spreadtrum USB driver software is essential. Find the correspondent firmware file that runs the Android device. Incorrect firmware always bricks/ damages devices instantly.

Important : Use "spdflashtool" as the password to unzip the files.

SPD Tool R21.0.0001 (Latest Version)
SPD Research Tool R21.0.0001
Download R19.0.0001 version
SPD Flash R17.0.0001
Download Tool for Bin Packet Error
SPD FlashTool R4.0.0001
SPD FlashTool R3.0.0001
SpreadTrum Upgrade Tool R2.9.9015
Download SpreadTrum R2.9.9009
SpreadTrum FlashTool R2.9.9008
Install SPD Flash R2.9.9005

How to Flash Android Smartphone with SPD UpgradeTool

step 01: Download SPD Flash latest version from above links.
step 02: Check/ update the SpreadTrum driver for your device. If you do not have the drivers install/ update it for the latest version.
step 03: Find and Get the ROM/ firmware [.pac] file according to your device.
step 04: unzip the downloaded file for the new folder.
step 05: Run SpreadTrum Upgrade tool. [.exe]
step 06: Connect your device, your device needs to be switched off
step 07: After connecting your device --> Load Pocket and select PAC/PAC5 file for the connected device.
step 08: Click/ Select “Start Downloading"
step 09: Follow the instruction appears and continue the flashing.
step 10: The device will reboot automatically during the flashing.
step 11: A successful flashing appears a passed message in green color on the tool.

Special Points to Remember

SPD Upgrade Tool and the Research Tool only compatible with Spreadtrum chipset installed smartphones.
Especially the research tool activates against only ".pac" files. This is not supported with ".p5c and pac.5c" firmware types.
Download and save the correct firmware to an easily reachable location.
Use a personal computer only to utilize SPD tools. An APK file format is not released.
All Windows versions compatible with the flash tool. Available to download SPD flash up to Windows 10.
Use only a recommended USB data cable to connect the mobile to the PC.
Unzip the downloaded folder before using the tool. Both WinRAR and 7Zip can use for unzipping.
Flash an Android can be harmful. Take a proper backup and use the correct stock firmware.
Flash custom recovery and root package cause voiding the device warranty.

Important Note for Android SPD Flash Download

If SpreadTrum upgrade tool gives an error Bin Packet, then download the latest version and new copy of SPD tool and .pac file according to your device. Most probably this happens from old versions and corrupted data.
The Research Tool also corrects the "Bin Packet Loar Error" but it does not compatible with ".p5c & pac.5c" file formats.
Keep in mind to write IMEI at the end of Spreadtrum stock flash. Checkout WriteIMEI/ Read&WriteIMEI tools.

SpreadTrum FlashTool Smartphone Flash Video Tutorial

The Spreadtrum flash tool comes with enhanced features and you can download this directly from the download section. Always download the latest available tools and drivers. That will be the most compatible version for your android smartphone.SPD Flash would like to thank spflashtool.com for delivering the information on SPD Upgrade tool and spdflash.com for SPD flash tool download links.

More Tools from Spreadtrum Inc

SPD FRP tool and SPD IMEI repair tool released by the Spreadtrum Communication Inc. Repair Androids is focused task of alternative tools. An advanced system protection can merge with FRP and IMEI Repair tools.

SPD FRP Tool

The SPD FRP represents Spreadtrum factory reset protection. The FRP system activates automatically on Android 5 Lollipop version to upwards. A Goole account is needed for the execution. If someone needs flashing the device without your confirmation, the device will automatically lock due to SPD FRP utility.

Boot the device to the recovery mode, press volume down, choose Reboot to Bootloader. Now the device will run in Fastboot mode. Connect the device to the SPD FRP running PC using a recommended USB data cable. Enter the respective number displays in the menu and press enter to handle SP FRP. Click here to download the FRP tool.

SPD IMEI Repair Tool

Download SPD IMEI Repair Tool on a Windows PC and execute the app. The instruction notes will prompt. Enter the IMEI number and click the save option. Reboot the device and once started, the tool will replace the IMEI number.

SPD flash tool released only for Spreadtrum Android flash. This also called Spreadtrum Upgrade Tool. Flash ".pac" firmware including versions ".p5c and pac.5c". The tool upgraded to the latest SPD Flash R21.0.0001 version improving the flash structure and flattening the UI more user-friendly. Compatibility with more languages and the LCD configuration features with special NV and userimg files. The best alternative tool is SPD Research Tool which released with the same features. Note that the research tool does not compatible with ".p5c and pac.5c" firmware types. Write IMEI is essential at the end of a successful stock recovery flash. Find and download the optimal stock (.pac) recovery file. The flash possible to brick devices and eliminate internal and external storages. Take a complete backup and remove SD card if available for the protection.

Special Thanks

SPD Flash Tool AKA Spreadtrum Upgrade Tool and SPD Research tool are created by Spreadtrum Communications Inc. Full credit goes them for the great development. Download SPD Flash Tool on Windows for Spreadtrum Android flash to repair software errors officially.

Technology First

SPD Research Tool – All Versions Download

Download SPD Research Tool SmartPhone Flash Tool works for Spreadtrum( SPD ) chipset stock firmware flash file install or flash easily. It allows flashing PAC firmware only to Spreadtrum devices, allows flash Recovery or custom recovery load Pac file, it allows verifying test the external memory, Ram, Emmc, Nand, it allows format device auto and manual, hard reset and ETC.

The tool is officially developed by Spreadtrum Communications Inc. The process is really easy and convenient. You don’t need hard and fast rules and tools to use it. The interface is also neat and clean. The whole process gets reliable when you find the best and latest version here and the leading steps are too simple after that. All you have to do is load the firmware in the tool and start downloading it. It takes really less time as it is efficient and fast.

Features Of SPD Research Tool

It allows you to easily flash PAC ROM and firmware on your SPD device. The process of flashing is very simple and easy.
It also allows you to easily flash PSC ROM and firmware on your SPD device.
You can flash custom recovery or stock recovery on your device by using this tool. But keep in mind you have the right recovery file for your device. The recovery file should be in.IMG format.
Check the RAM and internal storage of your SPD device.
Its User-friendly interface is one of the best features of this tool. Anyone can use this tool without having any knowledge about it.
If you want to Hard Reset or Format your SPD device. Then you can easily do it by using SPD Upgrade Tool.

Download Links All Versions

SPD_Research_Tool_R25.20.3901 | LATEST VERSION

SPD_Research_Tool_R24.0.0003

SPD_Research_Tool_R23.19.5101

SPD_Research_Tool_R23.19.3301

SPD_Research_Tool_R23.0.0001

SPD_Research_Tool_R22.19.1301

SPD_Research_Tool_R21.0.0001

SPD_Research_Tool_R19.0.0001

SPD_Research_Tool_R17.0.0001

SPD_Research_Tool_R8.0.0001

SPD_Research_Tool_R7.0.0001

SPD_Research_Tool_R6.0.0001

SPD_Research_Tool_R4.0.0001

SPD_Research_Tool_R3.15.4901

SPD_Research_Tool_R3.0.0001

SPD_Research_Tool_R2.10.1003

SPD_Research_Tool_R2.9.901

SPD_Research_Tool_R2.9.7017

SPD_Research_Tool_R2.9.6011

Mobile Flashing Drivers | MTK, SPD, ADB, CDC Qualcomm..
Miracle box Drivers for Windows 7,8 & 10 | 32 bit & 64 bit
Tecno Bootloader Unlock Files & Tutorial |
DriverPack Solution Offline 2021 Free Download | 26GB File
Free SamFirm A.I.O V1.4.3 by Mahmoud Salah

Research Download - SPD Flash Tool R24.0.0003 All Versions

https://www.gsmfirmware.net/2020/07/research-download-spd-flash-tool.html

What Is Research Download Tool?

What are the features of the research download tool, how to flash the firmware with research download tool, what are the contents of research download tool files.

What Are the Additional Details of the Research Download Tool Tool?

Download Link of Research Download - SPD Flash Tool.

Research download tool features list:.

Read Flash.
Write Flash.
Erase Flash.
Erase All Flash.
Modify Packet Files.
Repartition.
Keep Charge While Flashing.
Set Debug Level.
UART Download.
End of Download (Reset to Normal, Power Off, Dump Uboot Log).
Read Option (Read MCP Type, Read Chip UID, Read Partition).
Check Option (Check Match, DDR Check, EMMC Check, Self Refresh, Check Second Hand Memory).
Auto Comparison
Multi-Languages.
LCD Configuration.
Vol-Freq Turning.
UART Port Switch.
First of all, you need to download the required Flash Tool program and the firmware file according to your mobile device. If you have already downloaded it, then skip this step.
Now extract the compressed file of Flash tool with the latest version of WinRAR.
Right-click on the " ResearchDownload.exe " setup file and run it in administrator mode.
Click the Load Packet button in the upper left corner and select the .pac firmware file. Once you select the firmware file, the Flash tool will take some time to load the file, so be patient.
After successfully loading the firmware file into the tool, click the third " Start Downloading " button of the program.
Then turn off the mobile device, press the boot key (volume up + volume down), and connect to the computer.
As soon as you connect your mobile device to the computer, the flashing process starts, and after the flashing process is completed, you will see Previous Passed written in green in the progress bar.
Finally, disconnect your mobile device from the computer and turn on the power; For the first time since the flash, the mobile will take about five to ten minutes to power on.

What Are the Additional Details of the Research Download Tool?

SPD Research Tool R24.0.0003.rar
SPD Research Tool R23.19.5101.rar
SPD Research Tool R23.19.3301.rar
SPD Research Tool R23.0.0001.rar
SPD Research Tool R22.19.1301.rar
SPD Research Tool R21.0.0001.rar
SPD Research Tool R19.0.0001.rar
SPD Research Tool R17.0.0001.rar
SPD Research Tool R8.0.0001.rar
SPD Research Tool R7.0.0001.rar
SPD Research Tool R6.0.0001.rar
SPD Research Tool R4.0.0001.rar
SPD Research Tool R3.15.4901.rar
SPD Research Tool R3.0.900.rar
SPD Research Tool R3.0.0001.rar
SPD Research Tool R2.10.1003.rar
SPD Research Tool R2.10.1001.rar
SPD Research Tool R2.9.9017.rar
SPD Research Tool R2.9.9016.rar
SPD Research Tool R2.9.9015.rar
SPD Research Tool R2.9.9009.rar
SPD Research Tool R2.9.9008.rar
SPD Research Tool R2.9.9005.rar
SPD Research Tool R2.9.9001.rar
SPD Research Tool R2.9.8005.rar
SPD Research Tool R2.9.8004.rar
SPD Research Tool R2.9.7017.rar
SPD Research Tool R2.9.7009.rar
SPD Research Tool R2.9.7008.rar
SPD Research Tool R2.9.7007.rar
SPD Research Tool R2.9.7006.rar
SPD Research Tool R2.9.7003.rar
SPD Research Tool R2.9.7002.rar
SPD Research Tool R2.9.7001.rar
SPD Research Tool R2.9.6011.rar

Miracle Box (Thunder Edition) 2.82 Cracked By [GSM X TEAM]

Smart Key V1.0.2 (Smart Software) Crack Tool By GSM X Team

GSM Aladdin v2 1.34 / v2 1.37 [CRACKED!]

Ultimate Multi Tool (UMT) v1.3 CDMA Crack without Box By GSM X TEAM

GSM Aladdin v2 1.42 Crack by CrackingGSM Team

ZONG 4G BOLT+ Huawei E5573Cs-322 Unlock Firmware (21.333.64.02.1456)

Samsung MDM Remove Tool (EDL Mode) By PLUK-GSM

Asif Kamboh
China Phone
Combination
Crack Programs
FireHose File
Hardware Repair
Mobile Tools
Modem Files
Unofficial Tools

Tools Update

Firmware update, tutorial update, menu footer widget.

DMCA Policy
Privacy Policy

Official SPD/Unisoc Flash Tool

Upgrade Tool
Research Tool
Factory Tool

SPD Research Tool R2.10.1001

SPD Research Tool R2.10.1001, also known as Spreadtrum Research Tool, is a Windows utility that allows you to flash the firmware on mobile devices running Spreadtrum chipsets. It features a simple user interface, making it easy to use even for beginners. The tool supports various Spreadtrum-based devices, including smartphones, tablets, and feature phones.

SPD Research Tool R2.10.1001 for Windows

The SPD Research Tool R2.10.1001 (SpreadTrum Research Tool) is a Windows-based application developed explicitly for flashing or installing firmware on mobile devices powered by SpreadTrum/Unisoc chipsets.

Some of the Key features of the SPD Research Tool R2.10.1001 include:

Firmware Flashing : This core feature enables users to update or downgrade the firmware of a SpreadTrum-powered device. It allows the installation of official or custom firmware, providing an avenue to fix software glitches, enhance performance, or install new features.
PAC Firmware Support : The SPD Research Tool is specifically designed to work with .pac firmware files. These files contain all the necessary information to flash the device properly, including the operating system, user interface, and other essential components.
Multiple Languages : Understanding that users worldwide may require this tool, some versions offer support for various languages. This feature enhances accessibility, making it easier for non-English speakers to understand and use the tool.
Format and Reset : This function allows users to format the device or perform a factory reset. It can be a valuable solution to software-related problems, such as system crashes, unresponsiveness, or persistent errors, restoring the device to its original state.
Recovery Flashing : Flashing custom recovery images is a more advanced feature, allowing users more control over their device’s backup, restoration, and firmware installation. It enables the use of custom ROMs and other modifications to the system.
Error Handling : Designed with built-in error handling capabilities, the tool provides specific error codes and messages if something goes wrong during the flashing process. This assists in troubleshooting and guiding users in identifying and rectifying the issue.

Download the SPD Research Tool R2.10.1001

Frequently asked questions, what is spd research tool r2.10.1001.

SPD Research Tool R2.10.1001 is a small utility that is easy to use and can be used to flash the firmware on various Spreadtrum-powered devices, including smartphones, tablets, and feature phones. It can also be used to repair devices that are bricked or stuck in a boot loop.

How do I install SPD Research Tool R2.10.1001?

SPD Research Tool R2.10.1001 is a portable application, eliminating the need for installation on your computer. Download the Flash Tool onto your computer, extract the contents, and open the ResearchDownload.exe file to launch the program.

How to use SPD Research Tool R2.10.1001?

Is spd research tool r2.10.1001 free.

Yes, SPD Research Tool R2.10.1001 is generally offered free of charge for personal use. Technicians and individual users widely use it to flash the firmware on devices with SpreadTrum/Unisoc chipsets.

Is SPD Research Tool R2.10.1001 Safe?

Yes, SPD Research Tool R2.10.1001 is safe for PCs, laptops, and mobile devices. Furthermore, since this flash tool is an official release from the Unisoc Communications community, it ensures safety and security when deployed on your computing devices.

Where can I find compatible firmware?

Privacy Policy
Source Code

Download SPD-Research-Tool-R21_0_0001.zip

🗂️ file information, 🚀 sharing links, uploader profile.

💻Software
⚙️Firmware
📱 MC Product
🔑Reset Password
🙋FAQ
✊Manual
08 Sep 2022
1 Minute to read

UPGRADEDOWNLOAD_R21.0.0001

Updated on 08 Sep 2022

UPGRADEDOWNLOAD_R21.0.0001.rar

What's Next

New printer utility

Gsm Tool Box

Spd research download tool.

Download SPD Research Download Latest

SPD Research Download All Version

An official website of the United States government

Here’s how you know

Official websites use .gov A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS A lock ( Lock Locked padlock icon ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Entire Site
Research & Funding
Health Information
About NIDDK
Funding Process
About Funding Mechanisms
R21: Catalytic Tool & Technology Development in Kidney, Urologic, & Hematologic Diseases (Clinical Trial Not Allowed)

R21: Catalytic Tool & Technology Development in Kidney, Urologic, & Hematologic Diseases (Clinical Trial Not Allowed)

The catalytic tool and technology development in kidney, urologic, and hematologic diseases r21 at niddk.

NIDDK funds catalytic tool and technology development in kidney, urologic, and hematologic diseases through the R21 grant mechanism. The R21 provides funding of approximately $125,000 per year for 2 years. Strong applications will develop new tools or technologies in kidney, urology or hematology with broad utility beyond the applicant's own laboratory and ideally push the entire field forward. As such, applications are required to provide plans for making the proposed tool or technology available to the national research community.

The R21 is not intended to support the improvement of tools or technologies that have already been deployed in kidney, urologic, or hematologic science. Extensive preliminary data demonstrating feasibility is an indication that the proposal is beyond the scope of this program.
The R21 is not intended to support “mini-R01s” with a traditional hypothesis-driven research plan.

Prospective applicants are strongly encouraged to contact:

Daniel Gossett, Ph.D. NIDDK Small Business Programs, Translational Research, and Technology Development

Most recent NIDDK funding announcement: PAR-23-119

Related Programs

Consider the following programs if the R21 does not align with your research.

An official website of the United States government

Here’s how you know

Official websites use .gov A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS A lock ( Lock A locked padlock ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Grants and Funding: Extramural Programs (EP)

Last Reviewed: November 25, 2022

Find a Funding Opportunity

Comparing Popular Research Project Grants—R01, R03, and R21

This page discusses the three most common types of Research Projects (R) : the NIH standard independent R01, the smaller R03, and the exploratory/developmental research R21 activity codes.

For other types of grants, check Types of Funding Opportunities .

We strongly advise you to contact an NIAID program officer before you start to develop your application. He or she can advise you on whether your proposed project is appropriate for a particular grant type.

The main driver of your decision for one activity code over another should be the scientific scope of the work being proposed. Normally, R01-type projects are mature ideas with preliminary data supporting a hypothesis. R21 projects are usually high-risk/high-reward and require a high degree of innovation. R03 projects are usually descriptive and are used to generate hypotheses and data to support them.

Is an R01 Right for You?

An R01 is for mature research projects that are hypothesis-driven with strong preliminary data. R01s provide up to five years of support, with a budget that reflects the costs required to complete the project.

If you have strong preliminary data supporting your hypothesis, we recommend applying for an R01. For more on qualifying for an R01, refer to Determine Eligibility for NIAID Grants .

New investigators, when trying to determine whether submitting an R01 application is a good idea, consider the following:

Do you have strong preliminary data that support your hypothesis/hypotheses?
Is there a strong rationale for the proposed study?
Do you have a proven track record of experience in the field, including publications in scientific journals?
Do you or your collaborators have sufficient expertise to accomplish the goals of the proposed work?

Read Know Your Audience and Write Your Research Plan for more information about writing your application.

Reviewers are asked to consider that new investigators may have a more modest track record and publication record than established investigators. Peer reviewers are advised to look more at your potential than your past achievements. Also note that NIAID new investigators benefit from a more favorable payline for R01 applications.

For additional details, check Information for New Investigators .

Smaller Awards (R03, R21)

If your project is not ready for an R01, you can consider a two-year small grant (R03) or exploratory/developmental research grant (R21) to generate preliminary data or develop approaches that could support a hypothesis that can be tested under the R01 activity code. If you are considering either of these activity codes, get more advice from a program officer before applying.

R03 Is Small

Don't let the word "small" fool you into thinking that an R03 is especially easy to get; it's not. Like most other grant activity codes, your application will have stiff competition, will undergo peer review, and must be suitable for the activity code.

Your project must be tightly focused, able to be completed in two years, and manageable with a maximum of $100,000 in direct costs over the two-year period. If your project doesn't meet these criteria, it's not likely to be well received by reviewers.

Examples of projects that fit the R03 include:

Pilot or feasibility studies
Descriptive studies
Secondary analysis of existing data
Small, self-contained research projects
Adaption or further development of research methodology or new research technology

To see the type of projects that have been funded, go to NIH RePORTER and select R03 in the Activity Code field. Also refer to R03 Sample Applications and Summary Statements .

New Investigators: R03 Might Not Be Your Best Option

At first glance, the R03 seems well suited to a new investigator. You can request up to $50,000 a year in direct costs and do not need preliminary data. And for someone who's never written a grant application, the shorter six-page Research Strategy (versus 12 pages for an R01) might be appealing.

That said, however, the smaller page limit means you need a concise, tightly focused research plan. The short time provided to complete the project and the limited budget mean you have little room for course correction.

Thus, when considering the R03 activity code, be sure to think about the scope of the research you are proposing, paying special attention to the timeline of the project and the funds that will be needed to complete the project.

Should You Apply for an R21?

The R21 activity code is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development. NIH has standardized the exploratory/developmental grant (R21) application characteristics, requirements, preparation, and review procedures in order to accommodate investigator-initiated (unsolicited) grant applications.

R21 projects are usually highly innovative driving the high-risk/high-reward principle that is characteristic of this activity code. R21 awards are intended to allow short duration funding (two years) for innovative ideas. R21 projects should be distinct from those supported through the traditional R01 and are not intended as a bridge between training and obtaining an R01 grant.

Here we lay out some considerations you'll want to pay attention to if you're thinking about submitting an R21 application.

R21 Pros and Cons

Allows you to introduce novel scientific ideas, model systems, tools, agents, targets, and technologies that have the potential to substantially advance biomedical research.
Preliminary data are not required for an R21 application.
If you're applying for an R21 to generate preliminary data, you could end up coming up short for time with a two-year grant.
In addition, the purpose of the R21 activity code is not necessarily to support hypothesis-based research.
Further, your R21 won't benefit from our higher R01 payline for new and early-stage investigators.

For a comparison of several key characteristics of R21s and R01s, see the next section.

R21 or R01?

This table compares some features of the parent R21 and R01 fund opportunity announcements (NOFOs). Note that institutes may publish their own funding opportunities (initiatives) using the R21 or R01 activity codes with different characteristics.

* Data come from RePORT's Research Project Success Rates for NIAID .

No matter which funding opportunity you choose, you are advised to discuss with your program officer to make sure you are applying to the appropriate NOFO. Also, you need to consider where your financial support will come from should you have a funding gap while awaiting receipt of an NIH award. Read more in Approaches for Staying Funded .

To find information about different activity codes, go to NIH's Types of Grant Programs page.

Previous Step

Have questions.

A program officer in your area of science can give you application advice, NIAID's perspective on your research, and confirmation that NIAID will accept your application.

Find contacts and instructions at When to Contact an NIAID Program Officer .

Login/Register

Server Service
IMEI Service
Credit Service

SPD Research Tool R25.20.3901 (Latest version)

SPD Research Tool is an official .pac firmware flasher tool on SPD/Unisoc powered devices. It helps to flash official stock ROM and FRP reset files on your devices.

On the current page, you will get the direct link to download Research Download Tool for Windows. We have shared the tool as a zip package, including the SPD/Unisoc USB Driver.

Download SPD Research Tool

Latst Update: 16th Feb 2024

Advantage Of This Tool

Flash Multiple Devices: At the same time, you can flash multiple same devices using SPD Research Tool.

Reset FRP Lock: You can easily reset the FRP lock by flashing the FRP file using this tool.

Easy To Use: The tool’s UI is very simple. This makes the tool very easy to use.

Portable Application: It is a portable Application. There is no need to install it on your computer.

How To Flash Stock ROM Using SPD Research Tool?

Download SPD Research Tool on your computer.
Then, install SPD USB Driver. If already installed, then skip this step.
Firstly, open the tool. Then follow the following steps.
Now, click on the Load packet button and choose .pac stock ROM.
After loading the stock ROM on the tool, click the Start downloading button.
Now, press the volume up + volume down buttons together and connect the device via a USB cable.
Wait a few minutes to complete flashing/installing.

Readme Once

Recommend: We recommend using the latest version of the SPD Research Tool. Because some latest device doesn’t support the old version.

Scan: The tool has no virus/malware. Because multiple virus detection engine has scanned it. Then, we upload it to our site.

Credit: Full credit goes to Spreadtrum Communications INC. Because they created and distributed this tool for free.

SPD/Unisoc USB Driver: If you are looking for SPD/Unisoc USB Driver for Windows. Then, click here to get SPD/Unisoc USB Driver .

GSM Manager is one of the best websites for activating or renewing flashing Box, Dongle, and Tools.

Our Privacy Policy

Our Refund Policy

Term and Condition

Part 1. Overview Information

National Institutes of Health ( NIH )

National Institute on Aging ( NIA )

National Institute on Alcohol Abuse and Alcoholism ( NIAAA )

National Institute of Biomedical Imaging and Bioengineering ( NIBIB )

Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD )

National Institute on Deafness and Other Communication Disorders ( NIDCD )

National Institute on Drug Abuse ( NIDA )

National Institute of Mental Health ( NIMH )

National Institute of Neurological Disorders and Stroke ( NINDS )

National Center for Complementary and Integrative Health ( NCCIH )

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Office of Behavioral and Social Sciences Research ( OBSSR )

R21 Exploratory/Developmental Research Grant

Reissue of RFA-EY-18-001 - BRAIN Initiative: New Concepts and Early - Stage Research for Large - Scale Recording and Modulation in the Nervous System (R21 Clinical Trial Not Allowed)

September 20, 2023 - This RFA has been reissued as RFA-EY-23-001
February 8, 2023 - Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed). See Notice NOT-NS-23-036
February 8, 2023 - Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed). See Notice NOT-NS-23-035
NOT-OD-23-012 Reminder: FORMS-H Grant Application Forms and Instructions Must be Used for Due Dates On or After January 25, 2023 - New Grant Application Instructions Now Available
NOT-OD-22-190 - Adjustments to NIH and AHRQ Grant Application Due Dates Between September 22 and September 30, 2022
October 28, 2021 - Reminder: FORMS-G Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2022 - New Grant Application Instructions Now Available. See Notice NOT-OD-22-018 .
September 13, 2021 - Updates to the Non-Discrimination Legal Requirements for NIH Recipients. See Notice NOT-OD-21-181 .
August 5, 2021 - New NIH "FORMS-G" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2022. See Notice NOT-OD-21-169
August 5, 2021 - Update: Notification of Upcoming Change in Federal-wide Unique Entity Identifier Requirements. See Notice NOT-OD-21-170
April 20, 2021 - Expanding Requirement for eRA Commons IDs to All Senior/Key Personnel. See Notice NOT-OD-21-109

See Section III. 3. Additional Information on Eligibility .

93.867, 93.213, 93.242, 93.866, 93.286, 93.279, 93.273, 93.853, 93.865, 93.173

This FOA seeks applications for unique and innovative recording and/or modulation technologies that are in the earliest stage of development, including new and untested ideas that are in the initial stages of conceptualization. Some projects may aim to increase recording or modulation capabilities by many orders of magnitude, while others may aim to improve the precision and selectivity of recording or modulation (also referred to as stimulation, perturbation, or manipulation). A wide range of modalities are appropriate including acoustic, chemical, electrical, magnetic, optical and chemical, as well as the use of genetic tools.

Invasive or non-invasive approaches are sought that will enable large-scale recording and/or precise manipulation of neural activity, and that would ultimately be compatible with experiments in humans or behaving animals. Applications are encouraged from any qualified individuals, including physicists, engineers, theoreticians, and scientists, especially those not typically involved with neuroscience research.

Not Applicable

May 3, 2021; October 29, 2021; May 2, 2022; October 28, 2022; May 1, 2023; October 27, 2023

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

August 2021, January 2022, August 2022, January 2023, August 2023, January 2023

January 2022, May 2022, January 2023, May 2023, January 2024, May 2024

February 2022, June 2022, February 2023, June 2023, February 2024, June 2024

It is critical that applicants follow the instructions in the Research (R) Instructions in the SF424 (R&R) Application Guide , except where instructed to do otherwise (in this FOA or in a Notice from NIH Guide for Grants and Contracts ).

Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV . When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review.

Part 2. Full Text of Announcement

Section i. funding opportunity description.

The BRAIN Initiative

The B rain R esearch through A dvancing I nnovative N eurotechnologies (BRAIN) Initiative is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, will show how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat and prevent brain disorders.

NIH is one of several federal agencies involved in the BRAIN Initiative. Planning for the NIH component of the BRAIN initiative is guided by the long-term scientific plan, " BRAIN 2025: A Scientific Vision ," which details seven high-priority research areas and calls for a sustained federal commitment of $4.5 billion over 12 years. This FOA and other recently issued FOAs are based on careful consideration by the NIH of the recommendations of the BRAIN 2025 Report, and input from the NIH BRAIN Multi-Council Working Group. Videocasts of the NIH BRAIN Multi-council Working Group are available at http://www.braininitiative.nih.gov/about/mcwg.htm .

In addition to the National BRAIN initiative, the NIH continues to have a substantial annual investment in neuroscience research. The Institutes and Centers contributing to the NIH BRAIN Initiative ( http://braininitiative.nih.gov/ ) support those research efforts through investigator-initiated applications as well as through specific FOAs. Potential applicants to this FOA are strongly encouraged to contact Scientific/Program staff if they have any questions about the best FOA for their research.

To enable rapid progress in development of new technologies as well as in theory and data analysis, the BRAIN Initiative encourages collaborations between neurobiologists and scientists from statistics, physics, mathematics, engineering, and computer and information sciences; and NIH welcomes applications from investigators in these disciplines.

NIH encourages BRAIN Initiative applications from investigators that are underrepresented in the biomedical, behavioral, or clinical research workforce (see data at http://www.nsf.gov/statistics/showpub.cfm?TopID=2&SubID=27 and the most recent report on Women, Minorities, and Persons with Disabilities in Science and Engineering ). Such individuals include those from underrepresented racial and ethnic groups, those with disabilities, and those from disadvantaged backgrounds.

The BRAIN Initiative will require a high level of coordination and sharing between investigators. It is expected that BRAIN Initiative awardees will cooperate and coordinate their activities after awards are made by participating in Program Director/Principal Investigator (PD/PI) meetings and in other activities.

This FOA is related to the recommendations in sections II.2, II.3, and II.4 from the BRAIN 2025 Report. These three recommendations call for accelerated development of new large-scale recording technologies and tools for neural circuit manipulation. These new technologies and approaches will provide unprecedented opportunities for exploring how the nervous system encodes, processes, utilizes, stores, and retrieves vast quantities of information. A better understanding of this dynamic neural activity will enable researchers to seek new ways to diagnose, treat, and prevent brain disorders.

Achieving these goals requires the ability to record simultaneously from thousands or tens-of- thousands of neurons contributing to the dynamic activity in a neural circuit. The relevant activity may be in clusters of cells packed closely together or may be in widely distributed circuits. Current microelectrode and imaging technologies are limited in the number of cells from which activity can be isolated and sampled simultaneously, by the size or location of the area to be sampled, by the depth of penetration, and by the invasiveness of the technique that might prohibit their use in human experimentation. Non-invasive technologies suitable for use in humans are currently limited in spatial resolution and temporal dynamics, as well as in their reflection of on-going electrical activity in circuit elements. This FOA seeks entirely new ideas, concepts and/or approaches from physics and engineering, and biology, for how these limitations might be overcome to enable increased recording capabilities on the scale of one or more orders of magnitude beyond that of current technology.

This FOA is also related to the goals of the updated BRAIN 2.0 Report, which recommends expanding the functionality and integration of electrophysiological and neurochemical methods. The next generation of recording/modulation technology development should include efforts to improve cell-type and neurochemical specificity. Thus, an equally important goal of this FOA is to discover novel ideas for technology capable of precisely manipulating activity in circuits. Dissecting the function of neural circuits requires the ability to precisely activate or inactivate brain cells (both neuronal and non-neuronal) in order to investigate underlying mechanisms and demonstrate causality. Current technologies such as microstimulation and optogenetic approaches are limited in specificity, temporal dynamics, and by the invasiveness of the technique.

Applications are expected to propose the development of ideas in the earliest stages for entirely new approaches for neural recording and/or precise manipulation of neural activity. Such ideas could encompass unique and innovative combinations of existing technology that create a synergistic result. An important goal is to stimulate new thinking and concepts for accelerating development of novel technologies that break current barriers to neural recording and/or manipulation. In addition to experimental approaches, this FOA may support early-stage testing using calculations, simulations, computational models, or other mathematical techniques for demonstrating that the signal sources and/or measurement technologies are theoretically capable of meeting future demands. The support might also be used for building and testing phantoms, prototypes, in-vitro or other bench-top models in order to validate underlying theoretical assumptions in preparation for companion FOAs aimed at proof-of concept testing in animal models.

Applications are expected to propose research that will explore ideas in their earliest stages of development in order to be responsive to goals and objectives of this FOA. The following topics are non-responsive: i) further development of existing technology; ii) neurobiological hypothesis-testing; iii) validation and/or refinement of current technology; or iv) development of analytical methods to be applied to existing technology and/or data.

The technologies that would ultimately evolve from these new approaches should be compatible with experiments in humans and/or behaving animals and should dramatically improve capabilities in order to enable experiments that are currently not possible. Preliminary data are not required; however, they may be included if available.

Applications from individuals not usually associated with neuroscience research or teams that cross boundaries forming interdisciplinary collaborations capable of bringing new and untested ideas are particularly encouraged. Accordingly, applicants might consider, where appropriate, multi-PD/PI applications that integrate appropriate expertise, including but not limited to biological, chemical and physical sciences, engineering, computational modeling and statistics.

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this FOA.

Need help determining whether you are doing a clinical trial?

NIH intends to fund an estimated 10 awards per fiscal year, corresponding to a total of $3-4 million in new awards per year.

Application budgets may not exceed $400,000 total direct costs over a maximum three-year funding period. No more than $200,000 total direct costs may be requested in any single year.

The scope of the proposed project should determine the project period. The maximum project period is 3 years.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this FOA.

Section III. Eligibility Information

1. eligible applicants.

Higher Education Institutions

Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:

Hispanic-serving Institutions
Historically Black Colleges and Universities (HBCUs)
Tribally Controlled Colleges and Universities (TCCUs)
Alaska Native and Native Hawaiian Serving Institutions
Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education

Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations

Small Businesses
For-Profit Organizations (Other than Small Businesses)

Local Governments

State Governments
County Governments
City or Township Governments
Special District Governments
Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)

Federal Governments

Eligible Agencies of the Federal Government
U.S. Territory or Possession
Independent School Districts
Public Housing Authorities/Indian Housing Authorities
Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations
Regional Organizations
Non-domestic (non-U.S.) Entities (Foreign Institutions)

Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement , are allowed.

Applicant organizations

Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission.

Dun and Bradstreet Universal Numbering System (DUNS) - All registrations require that applicants be issued a DUNS number. After obtaining a DUNS number, applicants can begin both SAM and eRA Commons registrations. The same DUNS number must be used for all registrations, as well as on the grant application.
NATO Commercial and Government Entity (NCAGE) Code Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.
eRA Commons - Applicants must have an active DUNS number to register in eRA Commons. Organizations can register with the eRA Commons as they are working through their SAM or Grants.gov registration, but all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.
Grants.gov Applicants must have an active DUNS number and SAM registration in order to complete the Grants.gov registration.

Program Directors/Principal Investigators (PD(s)/PI(s))

All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide.

2. Cost Sharing

This FOA does not require cost sharing as defined in the NIH Grants Policy Statement.

3. Additional Information on Eligibility

Number of applications.

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

The NIH will not accept duplicate or highly overlapping applications under review at the same time. This means that the NIH will not accept:

A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
An application that has substantial overlap with another application pending appeal of initial peer review (see NOT-OD-11-101 ).

Section IV. Application and Submission Information

1. requesting an application package.

The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this FOA. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission

All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed.

Note: Effective for due dates on or after January 25, 2023, the Data Management and Sharing (DMS) Plan will be attached in the Other Plan(s) attachment in FORMS-H and subsequent application forms packages. For due dates on or before January 24, 2023, the Data Sharing Plan and Genomic Data Sharing Plan GDS) will continue to be attached in the Resource Sharing Plan attachment in FORMS-G application forms packages.

The following section supplements the instructions found in the SF424 (R&R) Application Guide and should be used for preparing an application to this FOA.

All instructions in the SF424 (R&R) Application Guide must be followed.

R&R or Modular Budget

The budget should include funds necessary for travel for up to two key personnel to participate in a BRAIN investigator meeting, lasting not more than two days and including up to two overnight stays, for each year of the project.

Other Plan(s):

Note: Effective for due dates on or after January 25, 2023, the Data Management and Sharing Plan will be attached in the Other Plan(s) attachment in FORMS-H and subsequent application forms packages. For due dates on or before January 24, 2023, the Data Sharing Plan and Genomic Data Sharing Plan GDS) will continue to be attached in the Resource Sharing Plan attachment in FORMS-G application forms packages.

All applicants planning research (funded or conducted in whole or in part by NIH) that results in the generation of scientific data are required to comply with the instructions for the Data Management and Sharing Plan. All applications, regardless of the amount of direct costs requested for any one year, must address a Data Management and Sharing Plan.

All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:

Research Strategy: The Research Strategy section should identify, where appropriate, the physical principles that will be exploited with the proposed new technology that will theoretically enable substantial improvement in recording and/or modulation of activity suitable for eventual use in humans or behaving animals. The description should also include, where appropriate, how calculations, simulations, computational models, or other mathematical or bench-top methods will be employed to show feasibility of the novel approach along with the theoretical limitations of the approach in terms of spatial extent, resolution, and temporal dynamics.

Resource Sharing Plan : Individuals are required to comply with the instructions for the Resource Sharing Plans as provided in the SF424 (R&R) Application Guide.

The following modifications also apply:

All applications, regardless of the amount of direct costs requested for any one year, should address a Data Sharing Plan.

Only limited Appendix materials are allowed. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide.

When involving human subjects research, clinical research, and/or NIH-defined clinical trials (and when applicable, clinical trials research experience) follow all instructions for the PHS Human Subjects and Clinical Trials Information form in the SF424 (R&R) Application Guide, with the following additional instructions:

If you answered Yes to the question Are Human Subjects Involved? on the R&R Other Project Information form, you must include at least one human subjects study record using the Study Record: PHS Human Subjects and Clinical Trials Information form or Delayed Onset Study record.

Study Record: PHS Human Subjects and Clinical Trials Information

Note: Delayed onset does NOT apply to a study that can be described but will not start immediately (i.e., delayed start). All instructions in the SF424 (R&R) Application Guide must be followed.

Foreign Institutions

Foreign (non-U.S.) institutions must follow policies described in the NIH Grants Policy Statement , and procedures for foreign institutions described throughout the SF424 (R&R) Application Guide.

3. Unique Entity Identifier and System for Award Management (SAM)

See Part 1. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov.

Part I. Overview Information contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday , the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons , NIH’s electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Policy on Late Application Submission.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the SF424 (R&R) Application Guide.

5. Intergovernmental Review (E.O. 12372)

This initiative is not subject to intergovernmental review.

All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement .

Pre-award costs are allowable only as described in the NIH Grants Policy Statement .

Applications must be submitted electronically following the instructions described in the SF424 (R&R) Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply Application Guide . If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII .

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile Component of the SF424(R&R) Application Package. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH. See Section III of this FOA for information on registration requirements.

The applicant organization must ensure that the DUNS number it provides on the application is the same number used in the organization’s profile in the eRA Commons and for the System for Award Management. Additional information may be found in the SF424 (R&R) Application Guide.

See more tips for avoiding common errors.

Upon receipt, applications will be evaluated for completeness and compliance with application instructions by the Center for Scientific Review and responsiveness by components of participating organizations , NIH. Applications that are incomplete, non-compliant and/or nonresponsive will not be reviewed.

Applications Involving the NIH Intramural Research Program

The requests by NIH Intramural Scientists will be limited to the incremental costs required for participation. As such, these requests will not include any salary and related fringe benefits for career, career conditional or other Federal employees (civilian or uniformed service) with permanent appointments under existing position ceilings or any costs related to administrative or facilities support (equivalent to Facilities and Administrative or F&A costs). These costs may include salary for staff to be specifically hired under a temporary appointment for the project, consultant costs, equipment, supplies, travel, and other items typically listed under Other Expenses. Applicants should indicate the number of person-months devoted to the project, even if no funds are requested for salary and fringe benefits.

If selected, appropriate funding will be provided by the NIH Intramural Program. NIH intramural scientists will participate in this program as PDs/PIs in accord with the Terms and Conditions provided in this FOA. Intellectual property will be managed in accord with established policy of the NIH in compliance with Executive Order 10096, as amended, 45 CFR Part 7; patent rights for inventions developed in NIH facilities are NIH property unless NIH waives its rights.

Should an extramural application include the collaboration with an intramural scientist, no funds for the support of the intramural scientist may be requested in the application. The intramural scientist may submit a separate request for intramural funding as described above.

Applicants are required to follow the instructions for post-submission materials, as described in the policy . Any instructions provided here are in addition to the instructions in the policy.

Section V. Application Review Information

1. criteria.

Note: Effective for due dates on or after January 25, 2023, the Data Sharing Plan and Genomic Data Sharing Plan (GDS) as part of the Resource Sharing Plan will not be evaluated at time of review.

Only the review criteria described below will be considered in the review process. Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system.

For this particular announcement, note the following:

The R21 exploratory/developmental grant supports investigation of novel scientific ideas or new model systems, tools, or technologies that have the potential for significant impact on biomedical or biobehavioral research. An R21 grant application need not have extensive background material or preliminary information. Accordingly, reviewers will emphasize the conceptual framework, the level of innovation, and the potential to significantly advance our knowledge or understanding. Appropriate justification for the proposed work can be provided through literature citations, data from other sources, or, when available, from investigator-generated data. Preliminary data are not required for R21 applications; however, they may be included if available.

The novel technology sought in this FOA is expected to be at the earliest stage of development, prior to empirical studies of proof-of-concept or preliminary data.

Reviewers will provide an overall impact score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed).

Reviewers will consider each of the review criteria below in the determination of scientific merit, and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field.

Significance

Does the project address an important problem or a critical barrier to progress in the field? Is the prior research that serves as the key support for the proposed project rigorous? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field ?

Investigator(s)

Are the PD(s)/PI(s), collaborators, and other researchers well suited to the project? If Early Stage Investigators or those in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project?

Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed?

Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the project? Have the investigators included plans to address weaknesses in the rigor of prior research that serves as the key support for the proposed project? Have the investigators presented strategies to ensure a robust and unbiased approach, as appropriate for the work proposed? Are potential problems, alternative strategies, and benchmarks for success presented? If the project is in the early stages of development, will the strategy establish feasibility and will particularly risky aspects be managed? Have the investigators presented adequate plans to address relevant biological variables, such as sex, for studies in vertebrate animals or human subjects?

If the project involves human subjects and/or NIH-defined clinical research, are the plans to address 1) the protection of human subjects from research risks, and 2) inclusion (or exclusion) of individuals on the basis of sex/gender, race, and ethnicity, as well as the inclusion or exclusion of individuals of all ages (including children and older adults) , justified in terms of the scientific goals and research strategy proposed?

Environment

Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?

As applicable for the project proposed, reviewers will evaluate the following additional items while determining scientific and technical merit, and in providing an overall impact score, but will not give separate scores for these items.

Protections for Human Subjects

For research that involves human subjects but does not involve one of the categories of research that are exempt under 45 CFR Part 46, the committee will evaluate the justification for involvement of human subjects and the proposed protections from research risk relating to their participation according to the following five review criteria: 1) risk to subjects, 2) adequacy of protection against risks, 3) potential benefits to the subjects and others, 4) importance of the knowledge to be gained, and 5) data and safety monitoring for clinical trials.

For research that involves human subjects and meets the criteria for one or more of the categories of research that are exempt under 45 CFR Part 46, the committee will evaluate: 1) the justification for the exemption, 2) human subjects involvement and characteristics, and 3) sources of materials. For additional information on review of the Human Subjects section, please refer to the Guidelines for the Review of Human Subjects .

Inclusion of Women, Minorities, and Individuals Across the Lifespan

When the proposed project involves human subjects and/or NIH-defined clinical research, the committee will evaluate the proposed plans for the inclusion (or exclusion) of individuals on the basis of sex/gender, race, and ethnicity, as well as the inclusion (or exclusion) of individuals of all ages (including children and older adults) to determine if it is justified in terms of the scientific goals and research strategy proposed. For additional information on review of the Inclusion section, please refer to the Guidelines for the Review of Inclusion in Clinical Research .

Vertebrate Animals

The committee will evaluate the involvement of live vertebrate animals as part of the scientific assessment according to the following criteria: (1) description of proposed procedures involving animals, including species, strains, ages, sex, and total number to be used; (2) justifications for the use of animals versus alternative models and for the appropriateness of the species proposed; (3) interventions to minimize discomfort, distress, pain and injury; and (4) justification for euthanasia method if NOT consistent with the AVMA Guidelines for the Euthanasia of Animals. Reviewers will assess the use of chimpanzees as they would any other application proposing the use of vertebrate animals. For additional information on review of the Vertebrate Animals section, please refer to the Worksheet for Review of the Vertebrate Animal Section .

Reviewers will assess whether materials or procedures proposed are potentially hazardous to research personnel and/or the environment, and if needed, determine whether adequate protection is proposed.

Resubmissions

As applicable for the project proposed, reviewers will consider each of the following items, but will not give scores for these items, and should not consider them in providing an overall impact score.

Applications from Foreign Organizations

Reviewers will assess whether the project presents special opportunities for furthering research programs through the use of unusual talent, resources, populations, or environmental conditions that exist in other countries and either are not readily available in the United States or augment existing U.S. resources.

Select Agent Research

Reviewers will assess the information provided in this section of the application, including 1) the Select Agent(s) to be used in the proposed research, 2) the registration status of all entities where Select Agent(s) will be used, 3) the procedures that will be used to monitor possession use and transfer of Select Agent(s), and 4) plans for appropriate biosafety, biocontainment, and security of the Select Agent(s).

Resource Sharing Plans

Reviewers will comment on whether the following Resource Sharing Plans, or the rationale for not sharing the following types of resources, are reasonable: (1) Data Sharing Plan ; (2) Sharing Model Organisms ; and (3) Genomic Data Sharing Plan (GDS) .

Authentication of Key Biological and/or Chemical Resources:

For projects involving key biological and/or chemical resources, reviewers will comment on the brief plans proposed for identifying and ensuring the validity of those resources.

Budget and Period of Support

Reviewers will consider whether the budget and the requested period of support are fully justified and reasonable in relation to the proposed research.

2. Review and Selection Process

Applications will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s) convened by the National Eye Institute, in accordance with NIH peer review policy and procedures , using the stated review criteria . Assignment to a Scientific Review Group will be shown in the eRA Commons.

As part of the scientific peer review, all applications will receive a written critique.

Applications may undergo a selection process in which only those applications deemed to have the highest scientific and technical merit (generally the top half of applications under review) will be discussed and assigned an overall impact score.

Applications will be assigned on the basis of established PHS referral guidelines to the appropriate NIH Institute or Center. Applications will compete for available funds with all other recommended applications submitted in response to this FOA. Following initial peer review, recommended applications will receive a second level of review by the National Advisory Eye Council. The following will be considered in making funding decisions:

Scientific and technical merit of the proposed project as determined by scientific peer review.
Availability of funds.
Relevance of the proposed project to program priorities.

3. Anticipated Announcement and Award Dates

Information regarding the disposition of applications is available in the NIH Grants Policy Statement .

Section VI. Award Administration Information

1. award notices.

A formal notification in the form of a Notice of Award (NoA) will be provided to the applicant organization for successful applications. The NoA signed by the grants management officer is the authorizing document and will be sent via email to the grantee’s business official.

Awardees must comply with any funding restrictions described in Section IV.5. Funding Restrictions . Selection of an application for award is not an authorization to begin performance. Any costs incurred before receipt of the NoA are at the recipient's risk. These costs may be reimbursed only to the extent considered allowable pre-award costs.

Any application awarded in response to this FOA will be subject to terms and conditions found on the Award Conditions and Information for NIH Grants website. This includes any recent legislation and policy applicable to awards that is highlighted on this website.

Institutional Review Board or Independent Ethics Committee Approval: Grantee institutions must ensure that protocols are reviewed by their IRB or IEC. To help ensure the safety of participants enrolled in NIH-funded studies, the awardee must provide NIH copies of documents related to all major changes in the status of ongoing protocols.

2. Administrative and National Policy Requirements

All NIH grant and cooperative agreement awards include the NIH Grants Policy Statement as part of the NoA. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General and Part II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Grantees, and Activities . More information is provided at Award Conditions and Information for NIH Grants .

Recipients of federal financial assistance (FFA) from HHS must administer their programs in compliance with federal civil rights laws that prohibit discrimination on the basis of race, color, national origin, disability, age and, in some circumstances, religion, conscience, and sex. This includes ensuring programs are accessible to persons with limited English proficiency. The HHS Office for Civil Rights provides guidance on complying with civil rights laws enforced by HHS. Please see https://www.hhs.gov/civil-rights/for-providers/provider-obligations/index.html and http://www.hhs.gov/ocr/civilrights/understanding/section1557/index.html .

HHS recognizes that research projects are often limited in scope for many reasons that are nondiscriminatory, such as the principal investigator’s scientific interest, funding limitations, recruitment requirements, and other considerations. Thus, criteria in research protocols that target or exclude certain populations are warranted where nondiscriminatory justifications establish that such criteria are appropriate with respect to the health or safety of the subjects, the scientific study design, or the purpose of the research. For additional guidance regarding how the provisions apply to NIH grant programs, please contact the Scientific/Research Contact that is identified in Section VII under Agency Contacts of this FOA.

Recipients of FFA must ensure that their programs are accessible to persons with limited English proficiency. HHS provides guidance to recipients of FFA on meeting their legal obligation to take reasonable steps to provide meaningful access to their programs by persons with limited English proficiency. Please see https://www.hhs.gov/civil-rights/for-individuals/special-topics/limited-english-proficiency/fact-sheet-guidance/index.html and https://www.lep.gov . For further guidance on providing culturally and linguistically appropriate services, recipients should review the National Standards for Culturally and Linguistically Appropriate Services in Health and Health Care at https://minorityhealth.hhs.gov/omh/browse.aspx?lvl=2&lvlid=53 .
Recipients of FFA also have specific legal obligations for serving qualified individuals with disabilities. Please see http://www.hhs.gov/ocr/civilrights/understanding/disability/index.html .
HHS funded health and education programs must be administered in an environment free of sexual harassment. Please see https://www.hhs.gov/civil-rights/for-individuals/sex-discrimination/index.html ; https://www2.ed.gov/about/offices/list/ocr/docs/shguide.html; and https://www.eeoc.gov/eeoc/publications/upload/fs-sex.pdf . For information about NIH's commitment to supporting a safe and respectful work environment, who to contact with questions or concerns, and what NIH's expectations are for institutions and the individuals supported on NIH-funded awards, please see https://grants.nih.gov/grants/policy/harassment.htm .
Recipients of FFA must also administer their programs in compliance with applicable federal religious nondiscrimination laws and applicable federal conscience protection and associated anti-discrimination laws. Collectively, these laws prohibit exclusion, adverse treatment, coercion, or other discrimination against persons or entities on the basis of their consciences, religious beliefs, or moral convictions. Please see https://www.hhs.gov/conscience/conscience-protections/index.html and https://www.hhs.gov/conscience/religious-freedom/index.html .

Please contact the HHS Office for Civil Rights for more information about obligations and prohibitions under federal civil rights laws at https://www.hhs.gov/ocr/about-us/contact-us/index.html or call 1-800-368-1019 or TDD 1-800-537-7697.

In accordance with the statutory provisions contained in Section 872 of the Duncan Hunter National Defense Authorization Act of Fiscal Year 2009 (Public Law 110-417), NIH awards will be subject to the Federal Awardee Performance and Integrity Information System (FAPIIS) requirements. FAPIIS requires Federal award making officials to review and consider information about an applicant in the designated integrity and performance system (currently FAPIIS) prior to making an award. An applicant, at its option, may review information in the designated integrity and performance systems accessible through FAPIIS and comment on any information about itself that a Federal agency previously entered and is currently in FAPIIS. The Federal awarding agency will consider any comments by the applicant, in addition to other information in FAPIIS, in making a judgement about the applicant’s integrity, business ethics, and record of performance under Federal awards when completing the review of risk posed by applicants as described in 45 CFR Part 75.205 Federal awarding agency review of risk posed by applicants. This provision will apply to all NIH grants and cooperative agreements except fellowships.

Data Management and Sharing

Note: The NIH Policy for Data Management and Sharing is effective for due dates on or after January 25, 2023.

Consistent with the NIH Policy for Data Management and Sharing, when data management and sharing is applicable to the award, recipients will be required to adhere to the Data Management and Sharing requirements as outlined in the NIH Grants Policy Statement . Upon the approval of a Data Management and Sharing Plan, it is required for recipients to implement the plan as described.

3. Reporting

A final RPPR, invention statement, and the expenditure data portion of the Federal Financial Report are required for closeout of an award, as described in the NIH Grants Policy Statement .

The Federal Funding Accountability and Transparency Act of 2006 (Transparency Act), includes a requirement for awardees of Federal grants to report information about first-tier subawards and executive compensation under Federal assistance awards issued in FY2011 or later. All awardees of applicable NIH grants and cooperative agreements are required to report to the Federal Subaward Reporting System (FSRS) available at www.fsrs.gov on all subawards over $25,000. See the NIH Grants Policy Statement for additional information on this reporting requirement.

In accordance with the regulatory requirements provided at 45 CFR 75.113 and Appendix XII to 45 CFR Part 75, recipients that have currently active Federal grants, cooperative agreements, and procurement contracts from all Federal awarding agencies with a cumulative total value greater than $10,000,000 for any period of time during the period of performance of a Federal award, must report and maintain the currency of information reported in the System for Award Management (SAM) about civil, criminal, and administrative proceedings in connection with the award or performance of a Federal award that reached final disposition within the most recent five-year period. The recipient must also make semiannual disclosures regarding such proceedings. Proceedings information will be made publicly available in the designated integrity and performance system (currently FAPIIS). This is a statutory requirement under section 872 of Public Law 110-417, as amended (41 U.S.C. 2313). As required by section 3010 of Public Law 111-212, all information posted in the designated integrity and performance system on or after April 15, 2011, except past performance reviews required for Federal procurement contracts, will be publicly available. Full reporting requirements and procedures are found in Appendix XII to 45 CFR Part 75 Award Term and Conditions for Recipient Integrity and Performance Matters.

Section VII. Agency Contacts

We encourage inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants.

eRA Service Desk (Questions regarding ASSIST, eRA Commons, application errors and warnings, documenting system problems that threaten submission by the due date , and post-submission issues)

Finding Help Online: http://grants.nih.gov/support/ (preferred method of contact) Telephone: 301-402-7469 or 866-504-9552 (Toll Free)

General Grants Information (Questions regarding application instructions, application processes, and NIH grant resources) Email: [email protected] (preferred method of contact) Telephone: 301-637-3015

Grants.gov Customer Support (Questions regarding Grants.gov registration and Workspace) Contact Center Telephone: 800-518-4726 Email: [email protected]

Martha Flanders, PhD National Eye Institute (NEI) Telephone: 301-451-2020 Email: [email protected]

Brian Hoshaw, PhD National Eye Institute (NEI) Telephone: 301-451-2020 Email: [email protected]

Karen Robinson Smith National Eye Institute (NEI) Telephone: 301-435-8178 Email: [email protected]

Section VIII. Other Information

Recently issued trans-NIH policy notices may affect your application submission. A full list of policy notices published by NIH is provided in the NIH Guide for Grants and Contracts . All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement .

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 45 CFR Part 75.

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files .

IMAGES

SPD Research Tool R21.0.0001 for Windows
Download SPD Research Tool R21.0.0001 Free Download (all versions
Download SPD Research Tool R21.0.0001 Free Download (all versions
SPD Research Tool R21.0.0001 Download Latest Version Official Tool
Boiling curves. 1
SPD Upgrade Tool R21 0 0001, SPD Spreadtrum Latest Tool 2019

VIDEO

Flash advan nasa 5202
A second malaria vaccine has been approved!
20231216 Botnet Detection Live Streaming (300+ zombies detected)
20231219 Botnet Detection Live Streaming (300+ zombies detected)
20231215 Botnet Detection Live Streaming (300+ zombies detected)
20231228 Botnet Detection Live Streaming (400+ zombies detected)

COMMENTS

SPD Research Tool R21.0.0001
SPD Research Tool R21.0.0001. SPD Research Tool R21.0.0001, also known as Spreadtrum Research Tool, is a Windows utility that allows you to flash the firmware on mobile devices running Spreadtrum chipsets. It features a simple user interface, making it easy to use even for beginners. The tool supports various Spreadtrum-based devices, including ...
Download SPD Research Tool
Download SPD Research Tool (Spreadtrum) SPD Research Tool is compatible with all versions of Windows OS, including Windows XP to Windows 11 (x32 or x64 bit). If in case you were looking for the latest version of the Research Tool, then use the following links to get it on your computer: ... R21.0.0001: SPD_Research_Tool_R21..0001.zip. R22.19. ...
How to use SPD Research Tool
Now, Open ResearchDownload.exe to launch the Tool: Once Research Tool is Launched, you will be able to see the following window: Click on the Load Packet Button: Locate the .pac based Stock Firmware (ROM Flash File) on your Computer (assuming you have already downloaded the Stock Firmware in Step#2) and Click on Open to Load the Firmware ...
SPD Research Tool R21.0.0001
The SPD Research Tool R21.0.0001 is a Portable Application for Computer. It Helps to Easily SpreadTrum CPU install Firmware (Flash File). ... Download SPD Research Tool R21.0.0001 on your laptop and PC. Download The SPD USB Driver Zip File Package Extract it. Dabble click choose menu the driver and install. After opening the SPD Research (.exe).
SPD Research Tool R21.0.0001 Download
Oppo Realme Meta Mode Driver | Oppo Mtk Cdc Driver Download 2021 Lyf F320b Flash File (Stock Rom) Free Download | LYF-F320B-002-02-56-250322 Latest Version Firmware Estech Schematic V1.2.5 Free Download | One Year Free Shematic Diagram Tool Download
SPD Research Tool
Download SPD Research Tool SmartPhone Flash Tool works for Spreadtrum chipset stock firmware flash file install or flash easily. if you need the latest. ... SPD Research Tool R21.0.0001: Google Drive - Mega: SPD Research Tool R19.0.0001: Google Drive - Mega: SPD Research Tool R17.0.0001: Google Drive - Mega:
Unisoc / Spreadtrum Upgrade, Factory & Research Download Tools versions
22,062. 20-10-2016, 12:41 AM. #1. Below is a collection of all versions of Spreadtrum Research / Upgrade / Factory Download tool. They are Windows tools for flashing .pac files / firmware to Spreadtrum (SPD) Android phones.
SPD Flash Tool
The newly released SPD flash tool R21.0.0001 is now available to download. If any matter, use the latest version of SPD Research Tool to flash ".pac" firmware. Download and install the latest version of Spreadtrum USB driver software is essential. Find the correspondent firmware file that runs the Android device.
NIH Exploratory/Developmental Research Grant Award (R21)
Investigators are strongly encouraged to consult with the appropriate NIH program administrator about their proposed research project during the concept development stage of the application. All R21 grant applications will be assigned to the ICs according to standard PHS referral guidelines and specific program interests.
SPD_Research_Tool_R21.0.0001.zip
Download SPD_Research_Tool_R21..0001.zip. for the -Android- Utilities, by Five Corp. Click Here to Start Download. No wait time for you! Download right away. 0 secs. ... Download GApps, Roms, Kernels, Themes, Firmware, and more. Free file hosting for all Android developers.
SPD Research Tool
Download SPD Research Tool SmartPhone Flash Tool works for Spreadtrum ( SPD) chipset stock firmware flash file install or flash easily. It allows flashing PAC firmware only to Spreadtrum devices, allows flash Recovery or custom recovery load Pac file, it allows verifying test the external memory, Ram, Emmc, Nand, it allows format device auto ...
Research Download
Right-click on the " ResearchDownload.exe " setup file and run it in administrator mode. Click the Load Packet button in the upper left corner and select the .pac firmware file. Once you select the firmware file, the Flash tool will take some time to load the file, so be patient.
SPD Research Tool R2.10.1001
SPD Research Tool R2.10.1001, also known as Spreadtrum Research Tool, is a Windows utility that allows you to flash the firmware on mobile devices running Spreadtrum chipsets. It features a simple user interface, making it easy to use even for beginners. The tool supports various Spreadtrum-based devices, including smartphones, tablets, and ...
Download SPD-Research-Tool-R21_0_0001.zip
File URL: https://www.droidmirror.com/download/spd-research-tool-r21--0001-zip: HTML Code <a href="https://www.droidmirror.com/download/spd-research-tool-r21-0-0001 ...
PDF R21 Submission Checklist
R21 Submission Checklist All written attachments are identified below with an asterisk (*). Other components may include PDF forms or form fields. Additional guidance on the content and format of all documents is located in the SF424 Research Instructions for ... If your study meets the definition of human subj ects research, the required ...
UPGRADEDOWNLOAD_R21.0.0001
UPGRADEDOWNLOAD_R21.0.0001. Updated on 08 Sep 2022. 1 Minute to read. PDF.
RESEARCHDOWNLOAD_R21.0.0001.rar
RESEARCHDOWNLOAD_R21..0001.rar Firmware Iball iT-KSA0066 (BizniZ mini) Folder : Tools File Size: 7.81 MB Date 13-03-2020 11:13 PM Download File Now RESEARCHDOWNLOAD_R21..0001.rar Easy Firmware First Source Firmware in the world Firmware Downloads - All Official Android & Firmware Updates & Rom Updates Download Repair Firmware ( 4Files) Full ...
SPD Research Download Tool
Name Link; SPD Research Download R25.20.3901: Download: SPD Research Download R24.0.0003: Download: SPD Research Download R23.19.5101: Download: SPD Research Download ...
R21: Catalytic Tool & Technology Development in Kidney, Urologic
As such, applications are required to provide plans for making the proposed tool or technology available to the national research community. The R21 is not intended to support the improvement of tools or technologies that have already been deployed in kidney, urologic, or hematologic science.
Resources For R21 Reviewers
MECHANISM OF SUPPORT: This PA uses the NIH R21 mechanism. The applicant may request a project period of up to two years with a combined budget for direct costs of up $275,000 for the two year period. For example, the applicant may request $100,000 in the first year and $175,000 in the second year. The request should be tailored to the needs of ...
Comparing Popular Research Project Grants—R01, R03, and R21
If you mis-use the R21 activity code to support a small R01-type research project, you may find that two years is not long enough to complete a hypothesis-based project that yields enough data for publication or generates sufficient preliminary data for an R01 application.
SPD Research Tool R25.20.3901 (Latest version)
On the current page, you will get the direct link to download Research Download Tool for Windows. We have shared the tool as a zip package, including the SPD/Unisoc USB Driver. Download SPD Research Tool. Latst Update: 16th Feb 2024 . File Name: SPD_Research_Tool_R25.20.3901.zip; File Size: 10 MB; Version:
RFA-EY-21-001: BRAIN Initiative: New Concepts and Early-Stage Research
September 20, 2023 - This RFA has been reissued as RFA-EY-23-001; February 8, 2023 - Notice of Intent to Publish a Funding Opportunity Announcement for BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed). See Notice NOT-NS-23-036; February 8, 2023 - Notice of Intent to Publish a Funding ...

Download SPD Research Tool

Features of SPD Research Tool

Download SPD Research Tool (Spreadtrum)

ASMobile Downloader for Windows

MIO Kitchen for Windows, Linux and macOS

RockChip Android Tool for Windows

HQ MTK Customer Download Tool for Windows

Tiny Fastboot Script for Windows

SPD Research Tool R21.0.0001

SPD Research Tool R21.0.0001 Information

How To Install and Using SPD Research Tools?

Readme Once

Leave a Reply Cancel reply

Facebook SDK

You might like

SPD Research Tool – Download (All Versions) SPD Flash Tool

Feature Of SPD Research Tool

SPD Research Tool Download

How To Use SPD Research Tool

Leave a Comment Cancel reply

Download Factory / Research / Upgrade Download Tools (all versions)

Research Download Tool Versions

Upgrade Download Tool Versions

SPD Flash Tool - Download SPD Upgrade Tool

What is SPD Research Tool?

SpreadTrum Flash tool New Features

Flash .PAC firmware

Flash P5C Firmware

Supports Multi Languages

Download SPD Flash Tool

How to Flash Android Smartphone with SPD UpgradeTool

Special Points to Remember

Important Note for Android SPD Flash Download

SpreadTrum FlashTool Smartphone Flash Video Tutorial

More Tools from Spreadtrum Inc

SPD FRP Tool

SPD IMEI Repair Tool

Special Thanks

SPD Research Tool – All Versions Download

Features Of SPD Research Tool

Leave a Reply Cancel reply

Research Download - SPD Flash Tool R24.0.0003 All Versions

What Is Research Download Tool?

Download Link of Research Download - SPD Flash Tool.

What Are the Additional Details of the Research Download Tool?

Related Posts

Miracle Box (Thunder Edition) 2.82 Cracked By [GSM X TEAM]

Smart Key V1.0.2 (Smart Software) Crack Tool By GSM X Team

GSM Aladdin v2 1.34 / v2 1.37 [CRACKED!]

Ultimate Multi Tool (UMT) v1.3 CDMA Crack without Box By GSM X TEAM

GSM Aladdin v2 1.42 Crack by CrackingGSM Team

ZONG 4G BOLT+ Huawei E5573Cs-322 Unlock Firmware (21.333.64.02.1456)

Samsung MDM Remove Tool (EDL Mode) By PLUK-GSM

Tools Update

SPD Research Tool R2.10.1001

SPD Research Tool R2.10.1001 for Windows

Download the SPD Research Tool R2.10.1001

How do I install SPD Research Tool R2.10.1001?

How to use SPD Research Tool R2.10.1001?

Is SPD Research Tool R2.10.1001 Safe?

Where can I find compatible firmware?

Download SPD-Research-Tool-R21_0_0001.zip

UPGRADEDOWNLOAD_R21.0.0001

What's Next

Gsm Tool Box

SPD Research Download All Version

R21: Catalytic Tool & Technology Development in Kidney, Urologic, & Hematologic Diseases (Clinical Trial Not Allowed)

Related Programs

Grants and Funding: Extramural Programs (EP)

Find a Funding Opportunity

Comparing Popular Research Project Grants—R01, R03, and R21

Is an R01 Right for You?

Smaller Awards (R03, R21)

R03 Is Small

New Investigators: R03 Might Not Be Your Best Option

Should You Apply for an R21?

R21 Pros and Cons

R21 or R01?

Previous Step

Login/Register